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Adrenal insufficiency: These vital substances can support the adrenal glands during stress
Chronic stress can lead to adrenal insufficiency: the adrenal glands no longer produce sufficient stress hormones and as a result you are no longer able to cope with the challenges of everyday life.
Here you can find out which vital substances can support the adrenal glands and the stress response.
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What is adrenal fatigue?
The adrenal glands are hormone-producing glands located above the kidneys. They produce hormones that are important for the stress response, such as cortisol, aldosterone and adrenaline.
In adrenal insufficiency, the function of the adrenal glands is impaired and they no longer produce enough hormones. Adrenal insufficiency is usually caused by chronic stress: the adrenal glands become exhausted.
How do you recognize adrenal insufficiency?
When you have adrenal insufficiency, your body no longer reacts properly to all of life's challenges. Even everyday things become a major challenge. Adrenal insufficiency typically manifests itself in exhaustion, listlessness, dizziness, tiredness, difficulty concentrating, low stress resistance, depression and sleep disorders.
In conventional medicine, adrenal insufficiency is not a recognized disease and there is no test that can clearly diagnose adrenal insufficiency. For this reason, diagnosis is not easy. However, the level of various hormones and the cortisol level over the course of the day provide important clues to adrenal insufficiency. The cortisol level is normally high in the morning and falls over the course of the day. In adrenal insufficiency, this typical pattern is no longer recognizable.
Treatment of adrenal insufficiency
In the case of adrenal insufficiency, stress triggers should first be identified and eliminated as best as possible.
In addition, various vital substances can support the adrenal glands and at the same time make the body more resistant to stress.
B vitamins
B vitamins are also known as nerve vitamins because they support nerve function in various ways. When we are under chronic stress, our nerves are on edge. Unfortunately, in such a situation we usually do not reach for healthy nerve food , but rather for sweets and other unhealthy snacks. However, these are not only very low in nutrients, they also deprive the body of important nutrients that it so urgently needs in stressful situations.
Vitamin B1 can support the body’s stress response and lower cortisol levels.
Niacin (vitamin B3) is important for energy metabolism and thus supports the energy supply of nerve cells. It is also involved in the production of cortisol and aldosterone.
Pantothenic acid (vitamin B5) supports the adrenal gland in the production of cortisol. A deficiency in vitamin B5 can therefore weaken the adrenal gland. [1]
Vitamin B6 is important for the production of important neurotransmitters such as GABA, dopamine and serotonin.
Vitamin B12 can help normalize hormone production.
Learn more about B vitamins
magnesium
Magnesium can reduce the release of stress hormones such as adrenaline and noradrenaline. [2] However, when you are stressed, your need for magnesium is increased, so a deficiency can easily occur.
Vitamin C
Vitamin C is involved in the production of many hormones that are important for the stress response. Vitamin C also helps to reduce oxidative stress, which occurs more frequently when there is high stress. At the same time, when there is stress, there is an increased need for vitamin C and this important vitamin can easily be lacking. [3]
Vitamin D
Vitamin D is also involved in the production of hormones, such as the happiness hormone serotonin. A lack of vitamin D is associated with depression and anxiety. [4] Vitamin D therefore probably helps to improve mood when you are stressed.
Omega-3 fatty acids
Omega-3 fatty acids are particularly valuable in times of stress. They are a component of nerve cell membranes and are therefore of great importance for the function and health of nerve cells. There is also evidence that they can help with depression and are important for mood. [5]
Tryptophan
Tryptophan is an amino acid, a protein building block. Tryptophan is one of the rarest amino acids and is therefore easily lacking in the diet. The amino acid is a precursor to the happiness hormone serotonin. It is therefore important for mood and probably ensures that one can better withstand psychological strain caused by stress. [6]
Conclusion: Vital substances can effectively support the adrenal gland
Adrenal insufficiency is usually caused by chronic stress. Various vital substances such as magnesium, vitamin D, vitamin C, omega-3 fatty acids, B vitamins and tryptophan can support the stress response and make the body more resistant to stress. At the same time, stress increases the need for some of these vital substances, so they can easily be lacking in chronic stress.
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[1] https://www.jstage.jst.go.jp/article/bpb/31/6/31_6_1205/_pdf/-char/en
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452159/
[3] https://pubmed.ncbi.nlm.nih.gov/11862365/
[4] https://pubmed.ncbi.nlm.nih.gov/29649128/
[5] https://pubmed.ncbi.nlm.nih.gov/23390041/
[6] https://pubmed.ncbi.nlm.nih.gov/11862365/

Histamine intolerance: causes, symptoms & treatment
Histamine intolerance affects approximately 1% of the population. Those affected are sensitive to histamine and develop allergy-like symptoms after eating foods rich in histamine.
However, avoiding foods that contain histamine is very difficult to achieve in the long term. However, there are promising treatment approaches that can help to get the disease under control.
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What is histamine intolerance?
Histamine is a messenger substance produced by the body that controls inflammatory and defense processes, as well as gastrointestinal movements. Histamine is found in many foods, such as meat, fish, dairy products, cheese and red wine. The body can also produce histamine itself.
Histamine intolerance is caused by an imbalance between the formation and breakdown of histamine. The body has problems breaking down histamine. As a result, people with histamine intolerance are sensitive to foods rich in histamine. [1]
Causes of histamine intolerance
The body breaks down histamine using two different enzymes: histamine N-methyltransferase (HNMT) and diamonioxidase (DAO). It is believed that in people with histamine intolerance, DAO is not active enough.
There can be various reasons for the DAO enzyme not being active enough. Scientists suspect that genetics influence the enzyme's activity. It is also suspected that in Crohn's disease, not enough DAO enzyme is produced. Crohn's disease is therefore strongly associated with histamine intolerance.
Some medications, such as blood pressure medication and antidepressants, can also reduce the activity of the enzyme. Fermented foods, on the other hand, contain biogenic amines that can inhibit the breakdown of histamine.
Symptoms: How to recognize histamine intolerance
Since histamine activates inflammation, histamine intolerance leads to allergy and flu-like symptoms. Headaches and gastrointestinal complaints are also typical. Itching, redness of the face, rashes, watery eyes and a runny nose can also occur.
Treatment of histamine intolerance
If you have histamine intolerance, avoiding histamine in food can help relieve symptoms. However, since histamine is found in almost all foods, this is a big challenge.
There are also antihistamines that block histamine receptors and thus inhibit the effects of histamine.
In addition, the DAO enzyme can be taken in capsule form, which makes histamine-rich foods better tolerated.
Nutritional therapy for histamine intolerance
Nutrients can effectively support the treatment of histamine intolerance. Some nutrients can help to lower histamine levels by activating the DAO enzyme. This allows the body to break down histamine better and the symptoms are less severe.
These include vitamin C and vitamin B6, for example. Vitamin C is important for the function of the DAO enzyme. Therefore, it is not surprising that when vitamin C levels are low, the histamine level in the blood increases. [2]
Vitamin B6 supports the breakdown of histamine in a similar way. [3] The combination of vitamin C and vitamin B6 is particularly effective in histamine intolerance.
Calcium can also help with histamine intolerance. However, the mechanism is slightly different here. Calcium was used to relieve allergy symptoms before the introduction of antihistamines. It seems to limit the damage caused by high histamine levels by sealing blood vessel walls. This prevents large amounts of histamine from entering the tissue. This can relieve itching, rashes and redness. [4]
Conclusion: Nutrients can effectively support the treatment of histamine intolerance
Histamine fulfils important functions in the body. However, problems arise when it cannot be broken down sufficiently. In addition to a low-histamine diet, antihistamines and the intake of DAO enzyme, certain micronutrients can effectively support the treatment of histamine intolerance. Vitamin C and vitamin B6 are important for the function of the DAO enzyme. Calcium, on the other hand, helps to limit the damage caused by histamine.
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[1] https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0034-1367613
[2] https://pubmed.ncbi.nlm.nih.gov/7365537/
[3] https://pubmed.ncbi.nlm.nih.gov/3098085/
[4] https://pubmed.ncbi.nlm.nih.gov/7865873/

Magnesium thieves: medications, stimulants & more
Magnesium is an essential mineral that plays a very central role in metabolism. It is involved in over 300 enzyme reactions and is therefore also known as the master mineral. Magnesium is particularly important for nerve and muscle function and for maintaining bones.
Unfortunately, magnesium is often not enough in the diet. On average, women only consume 200 mg per day, men 250 mg. [1] The daily requirement is 300 - 400 mg, depending on age and gender. [2]
In addition, there are many magnesium thieves that further increase the need for magnesium. Therefore, it is not surprising that magnesium deficiency is widespread. Typical symptoms of magnesium deficiency are muscle cramps, tension and twitching, sleep problems and high sensitivity to stress.
Here we present the 5 biggest magnesium thieves.
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1) Medicines
Medications can rob the body of magnesium in various ways.
Some medications affect the pH level in the digestive tract. For example, proton pump inhibitors, also known as acid blockers, increase the pH level in the stomach, making it less acidic. Proton pump inhibitors are used to treat heartburn.
Unfortunately, the increased pH value reduces the solubility of magnesium compounds, which means they are not absorbed as well.
Other medications act on magnesium transporters, which are important for the absorption of magnesium into the cells. These include diuretics, which are also known as water-removing agents. Thiazides, which contain the active ingredient hydrochlorothiazide, are often used to treat high blood pressure. They promote the excretion of magnesium via the kidneys. [3]
Medications pose a risk to magnesium levels especially when they are used over a long period of time, i.e. for many months or even years.
2) Hormone preparations
Hormone preparations, especially the contraceptive pill, also rob magnesium. The hormones promote magnesium excretion. The risk of magnesium deficiency is particularly high here, as many women take the pill for many years. [4]
3) Luxury goods
Unfortunately, stimulants such as coffee, tea and alcohol are also major magnesium thieves. Coffee has a dehydrating effect and therefore promotes the excretion of not only magnesium, but also other minerals such as phosphorus, potassium and sodium. [5]
4) Sports
Sport is of course very healthy. But sport also represents a physical strain that increases the need for magnesium. In addition, sweating during sport causes large amounts of magnesium and other minerals to be excreted through the skin. [6]
In our article about micronutrients in sport , you will learn which nutrients you should pay particular attention to if you do a lot of sport.
5) Stress
When stressed, the body performs at its best. Stress hormones are also released. Magnesium increases stress resilience, but stress also uses up a lot of magnesium. [7] Stress also promotes sweating, which also causes more magnesium to be excreted. Stress therefore increases the need for magnesium in various ways.
In another article you will learn how you can strengthen yourself with nerve food during stressful times.
Conclusion: Magnesium thieves are everywhere
Nowadays, magnesium thieves are lurking everywhere. You can't always avoid them and it's not necessarily necessary. But it's important to know that they exist. Because a magnesium deficiency is easy to avoid. If you suspect a deficiency, you should check your magnesium status. Ahigh-quality magnesium supplement helps to prevent or correct a deficiency.
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[1] https://www.kup.at/kup/pdf/1046.pdf
[2] https://www.dge.de/forschung/referenzwerte/magnesium/
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539869/
[4] https://pubmed.ncbi.nlm.nih.gov/23852908/
[5] https://www.iiste.org/Journals/index.php/FSQM/article/view/15023
[6] https://pubmed.ncbi.nlm.nih.gov/17172008/
[7] https://www.ncbi.nlm.nih.gov/books/NBK507250/

The most potassium-rich foods: How to meet your needs
Potassium is an essential mineral that we must consume through our diet. It is the counterpart of sodium and therefore plays a central role in the regulation of blood pressure. Potassium is also needed for signal transmission in nerve cells.
You can learn more about this important nutrient in our detailed article on potassium .
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Potassium requirement
According to the German Nutrition Society (DGE), the daily requirement of potassium is 4000 mg. Breastfeeding women have an increased requirement of 4,400 mg. [1]
Here is a list of the 10 foods richest in potassium:
1. White beans
Beans and other legumes are among the best sources of potassium. White beans, for example, provide 558 mg per 100 g.
In addition, they contain plenty of vitamin B1 and folic acid and are good sources of numerous minerals such as iron, magnesium, zinc , copper and manganese. [2] For vegans, legumes are also an important source of protein.
2. Pistachios
Pistachios are not only a delicious snack but also very healthy! They provide 1025 mg of potassium per 100 g. They are also rich in vitamin B1 and vitamin B6, as well as the minerals magnesium, copper and manganese. [3] So you are doing yourself a favor if you choose pistachios instead of chips and chocolate.
3. Flaxseed
Flaxseeds are known as a local superfood for good reason. They not only provide plenty of healthy fiber but also lots of B vitamins (especially vitamin B1, vitamin B6 and folic acid) and magnesium. They also provide a whopping 813 mg of potassium per 100 g. [4] So there are many good reasons to include flaxseeds in your diet more often. They go well in bread, muesli, yogurt and salad.
4. Almonds
Almonds are also a good source of potassium: they provide 705 mg per 100 g. Almonds also provide plenty of vitamin E and vitamin B2 and are rich in magnesium and manganese. [5] Almonds are also a very healthy snack. They taste particularly good when roasted.
5. Squid
Unfortunately, squid is not for everyone, but it is a valuable source of many vitamins and minerals. Not only does it contain 637 mg of potassium per 100 g, but it also provides plenty of vitamin B2, vitamin B12 , iron, copper and selenium. [6] Aren't these many good reasons to try squid?
6. Avocado
Avocados provide 485 mg per 100 g, so they are also a good source of potassium. Avocados are also very rich in vitamin K and folic acid. You can eat them plain or add a little salt, pepper and lemon juice to make a delicious guacamole. [7]
7. Pork
Meat also provides considerable amounts of potassium. Pork, for example, contains
489 mg per 100 g. Even though pork doesn't have the best reputation, it still provides many other valuable nutrients such as vitamin B1, vitamin B3 and vitamin B6, as well as the minerals phosphate and selenium . [8] But of course you should pay attention to the quality of pork. By eating meat from species-appropriate animal husbandry, you are not only doing something good for the animal, but also for yourself.
8. Sweet potatoes
Sweet potatoes contain 475 mg of potassium per 100 g. They are also an excellent source of vitamin A, vitamin C and manganese. [9] Sweet potatoes taste good as fries or in soup.
9. Potatoes
Potatoes are also a relatively good source of potassium: they provide 421 mg per 100 g. The good old potato is also rich in vitamin C and vitamin B6. [10] It is very versatile and tastes good boiled, fried or baked.
10. Bananas
Bananas have a reputation for being particularly rich in potassium. In fact, they contain comparatively little potassium, with 358 mg per 100 g. But they still manage to make it to number 10.
Bananas are also a good source of vitamin C, vitamin B6 and manganese.
Conclusion: Most foods contain little potassium
Although potassium is found in many foods, they usually only provide a small portion of the daily requirement. Legumes, nuts and seeds, as well as avocados are among the best sources. A high-quality dietary supplement can help meet potassium requirements.
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[1] https://www.dge.de/forschung/referenzwerte/kalium/
[2] Beans, white, ripe seeds, raw Nutrition Facts & Calories (self.com)
[3] Nuts, pistachio nuts, raw Nutrition Facts & Calories (self.com)
[4] Seeds, flaxseed Nutrition Facts & Calories (self.com)
[5] Nuts, almonds [Includes USDA commodity food A256, A264] Nutrition Facts & Calories (self.com)
[6] Mollusks, cuttlefish, mixed species, cooked, moist heat Nutrition Facts & Calories (self.com)
[7] Avocados, raw, California Nutrition Facts & Calories (self.com)
[8] Pork, fresh, enhanced, loin, top loin (chops), boneless, separable lean only, raw Nutrition Facts & Calories (self.com)
[9] Sweet potato, cooked, baked in skin, without salt [Sweetpotato] Nutrition Facts & Calories (self.com)
[10] Potato, flesh and skin, raw Nutrition Facts & Calories (self.com)

Detoxify the body: These nutrients promote detoxification
Nowadays we are exposed to many pollutants such as heavy metals, fine dust, pesticides, herbicides and many other chemicals. They are found in food, in the air, in water, in packaging and cosmetics. And our bodies also produce many toxic metabolic products every day that we need to detoxify.
The body has many detoxification mechanisms. The problem is that it needs a lot of nutrients to detoxify. Not only are we exposed to more and more pollutants these days, but the nutrient density of food is also decreasing. As a result, the body often does not have enough nutrients to effectively get rid of toxins.
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Detoxify the body with nutrients
Diet plays an essential role in detoxification. It provides many nutrients that are important for detoxification. Nutrients support detoxification in various ways:
During detoxification, nutrients are also eliminated along with the toxins. This is especially true for detoxification treatments and chelation therapies for heavy metal detoxification. It is therefore important to ensure a particularly good supply of nutrients before and during a detoxification treatment.
Many nutrients are involved in detoxification processes. For example, the detoxification enzymes in the liver require a number of nutrients to function properly.
Many nutrients can bind nutrients and thus have a detoxifying effect.
Vitamin C
Vitamin C is a powerful antioxidant that protects against free radicals. It therefore helps to reduce oxidative stress that occurs during detoxification processes.
In addition, vitamin C activates liver enzymes that are involved in the detoxification process in the liver. [1]
Vitamin C also promotes lead detoxification and a good supply of vitamin C reduces lead toxicity. [2]
secondary plant substances
Secondary plant substances such as polyphenols, terpenes and alkaloids have an antioxidant effect. They can reinforce each other's effects and also influence the effectiveness of vitamin C. Flavonoids, for example, support the effectiveness of vitamin C. [3] Secondary plant substances are found in fruit and vegetables. Intense colors such as in berries, peppers and beetroot indicate a high content of secondary plant substances.
Curcumin
Curcumin is an ingredient in curcuma , a South Asian ginger plant also known as turmeric. Curcumin has cancer-preventing properties. It can also reduce inflammation and promotes the detoxification process. [4]
The detoxifying effect is due to the fact that curcumin is very bitter. This stimulates the production of stomach acid and digestion. It also stimulates the production of bile, which increases the excretion of toxins.
Alpha-lipoic acid
Alpha-lipoic acid is a sulfur-containing fatty acid. It is used in the treatment of diabetic neuropathy, but can also effectively support the detoxification process.
Alpha-lipoic acid serves as a coenzyme in numerous metabolic processes. It also acts as an antioxidant that helps fight free radicals. It can regenerate used antioxidants such as vitamin E, vitamin C, coenzyme Q10 and glutathione. Alpha-lipoic acid is found in meat and also in some vegetables. Alpha-lipoic acid is also available as a dietary supplement that requires a prescription.
Vitamin E
Vitamin E is a fat-soluble vitamin. It is also an antioxidant and is therefore an effective radical scavenger.
Vitamin E is important for the absorption of selenium and can enhance its antioxidant functions. Vitamin E is also involved in the detoxification of heavy metals, such as mercury. [5]
N-acetylcysteine and MSM
Cysteine is an amino acid that the body can produce to a limited extent from the amino acids methionine and serine.
Cysteine can form complexes with heavy metals, allowing them to be excreted. Cysteine is usually used in the form of N-acetyl-cysteine.
Cysteine and MSM (methylsulfonylmethane) both contain sulfur groups that help regenerate glutathione. [6] , [7] Glutathione is an antioxidant and a key detoxification molecule.
selenium
Selenium is important for the thyroid and has central functions in energy metabolism. It also plays an important role in glutathione metabolic pathways, thereby supporting detoxification.
Selenium can also bind heavy metals such as mercury, making them easier to detoxify. [8]
zinc
Zinc is a component of many enzymes and has antioxidant properties. It is also involved in the glutathione signaling pathway, which makes it an effective detoxification aid. [9]
iodine
Iodine supports detoxification by binding heavy metals and forming complexes with many pollutants.
Other elements of nutrition
Dietary fiber promotes detoxification by stimulating liver and gall bladder function. It also binds toxins in the intestines, making them easier to eliminate.
Vegetables, especially green leafy vegetables, can also promote detoxification. The green color is due to the plant pigment chlorophyll, which can bind many pollutants. This is why the microalgae chlorella is so popular for detoxification.
Conclusion: Nutrients are essential detoxification aids
The body needs a lot of nutrients to detoxify effectively. A high level of toxicity therefore deprives the body of nutrients. If the diet does not provide enough nutrients, deficiencies can arise. A targeted intake of certain vitamins, minerals and secondary plant substances can effectively support detoxification.
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[1] https://www.scirp.org/journal/paperinformation.aspx?paperid=102322
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875841/
[3] https://pubmed.ncbi.nlm.nih.gov/30044505/
[4] https://pubmed.ncbi.nlm.nih.gov/20229497/
[5] http://www.foodsciencejournal.com/archives/2017/vol2/issue3/2-3-25
[6] https://www.nature.com/articles/srep30033
[7] https://pubmed.ncbi.nlm.nih.gov/21899544/
[8] https://pubmed.ncbi.nlm.nih.gov/1304229/
[9] https://pubmed.ncbi.nlm.nih.gov/7241230/

HPU – the underestimated metabolic disorder
HPU is a widespread metabolic disorder that, unfortunately, many doctors, therapists and alternative practitioners know little about.
Diagnosing HPU is the biggest hurdle. Because once HPU is confirmed as the cause of the symptoms, HPU can be treated very well with simple means.
Here you will learn what HPU is, what causes it and what successful therapy looks like.
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What is HPU?
HPU stands for hemopyrrollactamuria and is a widespread metabolic disorder.
In short, HPU causes problems in the production of heme. Heme forms the center of hemoglobin, the red blood pigment. Heme binds oxygen and is responsible for the oxygen supply.
In people with HPU, in addition to the normal, functional heme, a defective heme is also produced, known as hydroxyhemopyrrole-2-1. This defective heme must be excreted in the urine, for which the body needs vitamin B6, zinc and also some manganese. As a result, people with HPU have an increased need for these nutrients and a deficiency can easily occur.
An estimated 10% of women and 1% of men are affected by HPU. [1]
HPU causes
Since HPU occurs frequently in families, it is strongly assumed that this metabolic disorder is genetic.
It is suspected that there are also acquired forms; that is, that HPU can also be triggered or exacerbated by certain environmental factors.
Cervical spine trauma
According to mitochondrial expert Dr. Budo Kuklinski, there is a connection between cervical spine trauma and pyrrole excretion. Dr. Kuklinski was also able to show that people with cervical spine trauma often have a deficiency in zinc and vitamin B6.
When the cervical spine is injured, high concentrations of nitric oxide (NO) are formed. Large amounts of NO damage the mitochondria (the power plants of our cells). This is said to impair the mitochondria's energy production and disrupt heme formation. [2]
Heavy metal pollution
There appears to be a connection between HPU and high levels of heavy metals, but it is not clear how heavy metals can promote HPU. It is known that heavy metals can trigger gene and enzyme defects. It is therefore conceivable that heavy metals damage enzymes that are involved in heme formation and thus trigger HPU.
People with HPU also often have problems detoxifying heavy metals. And high levels of heavy metal exposure place additional strain on the detoxification system. [3]
HPU symptoms
HPU damages the body in two ways:
Leads to a lack of essential nutrients
In order to detoxify the defective heme, the body needs vitamin B6, zinc and manganese. This can easily lead to a deficiency in these nutrients. However, these nutrients are very important for the body. If the body does not have enough of them, health problems will arise sooner or later.
It increases the toxic load
Because people with HPU lack the nutrients they need for detoxification, they often have problems with the effective elimination of toxins. This can lead to an accumulation of toxins in the body, which can cause numerous damages. Heavy metals, for example, can change the genetic makeup and damage the mitochondria.
The following symptoms are typical for HPU:
Exhaustion and low resilience
poor stress resistance
anxiety
Forgetfulness and short short-term memory
high sensitivity to light and noise
missing dream recall
severe morning sickness
Anemia
mild hypoglycemia
Allergies and food intolerances
Many of these symptoms are non-specific, meaning that they can have many causes and cannot be clearly attributed to HPU. However, if many of these symptoms occur together, this can be an indication of HPU. To better classify the symptoms, there is an online HPU questionnaire .
HPU consequences
HPU also appears to increase the risk of some diseases. HPU is suspected to be involved in the development of the following diseases:
Thyroid dysfunction
Hashimoto's thyroiditis
ADD/ADHD
Tendency to addictive behavior
infertility
mental illnesses such as depression, panic attacks and severe mood swings
migraine
Diabetes type 2
Mitochondrial diseases
HPV Test
The defective heme (hydroxyhemopyrrole-2-1) is excreted in the urine and can be detected there.
A laboratory in the Netherlands offers HPU test kits. These can be ordered on the website: https://www.keac.nl/
It is important not to supplement zinc or vitamin B6 a few weeks before the test, as this can distort the result.
HPU therapy plan
In the treatment of HPU, dietary supplements with vitamin B6, zinc and manganese play a central role. If the body has sufficient amounts of these nutrients, it can detoxify the defective heme well and at the same time these nutrients are not lacking elsewhere. There are also combination preparations that contain all three nutrients. It is important to ensure that the preparation contains active vitamin B6 (pyridoxal-5-phosphate), as people with HPU often have difficulty converting inactive forms into active vitamin B6.
In addition to vitamin B6, zinc and manganese, other nutrients may also be useful.
A vitamin B complex is advisable because B vitamins work closely together.
Magnesium is needed for the activation of B vitamins and for energy production. Magnesium deficiency is widespread.
Coenzyme Q10 is important for mitochondrial metabolism and can improve energy balance.
Selenium , MSM (or N-acetylcysteine) and molybdenum can support detoxification.
Chlorella, coriander and wild garlic can also improve detoxification. They bind toxins, making them easier to excrete.
Conclusion: A good supply of nutrients is essential for HPU
In HPU, defective heme is formed. The body needs zinc, vitamin B6 and manganese to detoxify this heme. People with HPU therefore have an increased need for these three nutrients. A dietary supplement with zinc, vitamin B6 and manganese can support the detoxification of the defective heme. At the same time, it can counteract a deficiency in these three nutrients.
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[1] https://www.amazon.de/gp/product/B00Q6K7DHQ/ref=kinw_myk_ro_title
[2] https://www.dr-kuklinski.info/das-hws-trauma/
[3] https://www.baumeister-jesch.de/wp-content/uploads/hpu-englisch-flyer.pdf

Taurine: function, effect and dosage
You probably know taurine as an ingredient in Red Bull. Even though taurine unfortunately doesn't give you magical wings, it still has a lot to offer
Here you will learn what important functions taurine provides in the body and what it can potentially help with
And don’t worry, the fact that taurine is obtained from ox semen is fortunately just a rumor!
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What is taurine?
Taurine is an amino acid-like compound that is found primarily in the brain, eyes, heart and muscles. However, taurine is not a component of proteins.
Taurine has important functions in electrolyte balance and stimulates calcium concentration in cells. It also plays an important role in the nervous system and is an antioxidant . Taurine is also important for energy metabolism and for the mitochondria. Since it is a component of bile, taurine is also very important for fat digestion.
During embryonic development, taurine is needed for the development of the central nervous system and the heart. [1]
Taurine was once extracted from the bile of animals, but it is now produced synthetically as an ingredient in dietary supplements and energy drinks.
The effect of taurine
Some of the effects of taurine are currently being scientifically investigated. [2]
Promising against heart failure
There is exciting data on taurine in heart failure.
In a randomized clinical trial with 14 patients with heart failure, the subjects received either 6g of taurine or a placebo daily for 4 weeks. In the placebo group, the heart function of 4 subjects deteriorated. In the taurine group, heart function improved significantly. [3]
Taurine has a similar effect on the heart as AT2 antagonists and beta-blockers – two drugs used to treat heart failure. [4] Taurine also supports cardiac function by regulating calcium levels in the heart.
In Japan, taurine is officially approved for the treatment of heart failure.
Could help with high blood pressure
High blood pressure is also known as the “silent killer” because it usually causes no symptoms but dramatically increases the risk of heart attack, stroke and heart failure.
There is evidence that taurine may help treat high blood pressure.
In a study with 120 subjects with slightly elevated blood pressure, the participants received either 1.6 g of taurine or a placebo daily for 12 weeks. Taurine was able to significantly reduce blood pressure. The reduction in blood pressure was greatest in subjects who had the highest blood pressure at the start. [5]
Could improve athletic performance
Energy drinks like Red Bull contain taurine and are said to be able to increase performance. However, it is not possible to say whether this is due to taurine, the high caffeine content or other ingredients.
However, taurine is important for muscle function. Some studies have investigated whether taurine supplementation has an impact on athletic performance. [6]
In a study with endurance runners, the subjects were able to run 3 kilometers in a shorter time after taking 1 g of taurine. [7]
In another study, the muscle strength of subjects who took taurine supplements increased. At the same time, muscle soreness and oxidative damage in the muscles decreased.
Other possible uses of taurine
There are indications that taurine could help with certain diseases and conditions. These include certain eye diseases, cardiac arrhythmias, chronic inflammatory diseases and metabolic diseases. Unfortunately, there is very little solid data available so far.
Foods with taurine
The body can produce taurine itself from the amino acid cysteine, but in certain diseases, such as kidney and heart failure, there is an increased need and a deficiency can occur. Taurine is therefore said to be "semi-essential". An additional intake of taurine from outside (through food or nutritional supplements) helps to ensure an adequate supply.
Taurine is found in meat, fish and dairy products. [8] Vegans are therefore at increased risk of deficiency.
Taurine is also added to many energy drinks, such as Red Bull. However, due to the many additives, these are not recommended as part of a healthy diet.
Newborns cannot produce taurine themselves. However, breast milk contains taurine and it is also added to infant formula.
Most people consume 40 – 400 mg of taurine daily through their diet. [9]
Dosage of taurine
For dietary supplements, the recommended dosage is usually 500 – 2000 mg per day. 3000 mg daily is considered safe in the long term and no side effects are known at this dosage. [10]
However, if you have kidney disease, you should be careful when supplementing with taurine. In this case, it is best to talk to your doctor first.
When it comes to taurine as a dietary supplement, you should definitely pay attention to quality, because unfortunately there are many black sheep on the market. Make sure that the product is free of toxic extraction residues, gelling agents such as carrageenan and nanoparticles, sweeteners and sugar substitutes.
Conclusion: Taurine is a very versatile, important nutrient
Taurine is an important nutrient that our body can only produce to a limited extent and that has many important functions. An additional intake could be particularly helpful for certain chronic diseases. When supplementing with taurine, you should definitely choose a high-quality product.
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[1] https://pubmed.ncbi.nlm.nih.gov/12514918/
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933890/pdf/bt-26-225.pdf
[3] https://pubmed.ncbi.nlm.nih.gov/3888464/
[4] https://pubmed.ncbi.nlm.nih.gov/23722414/
[5] https://pubmed.ncbi.nlm.nih.gov/26781281/
[6] https://cdnsciencepub.com/doi/abs/10.1139/apnm-2012-0229
[7] https://pubmed.ncbi.nlm.nih.gov/22855206/
[8] https://pubmed.ncbi.nlm.nih.gov/2352336/
[9] https://web.archive.org/web/20060623112948/http://ec.europa.eu/food/fs/sc/scf/out22_en.html
[10] Taurine Uses, Benefits & Dosage - Drugs.com Herbal Database

The zinc-richest foods: How to meet your needs
Zinc is an essential mineral that we must consume through our diet. It is important for immune function, plays an important role in wound healing and is involved in over 300 enzymatic reactions.
In our detailed article about zinc you will learn more about why this mineral is so important.
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Zinc requirement
According to the German Nutrition Society (DGE), the daily requirement for zinc is approximately 7 to 16 mg per day. Pregnant and breastfeeding women have an increased need for zinc. The requirement also depends on the amount of phytic acid in the diet. Phytic acid is found primarily in grains and pulses and binds zinc, which increases the requirement.
Here is a list of the foods richest in zinc:
1. Oysters
This French delicacy takes some getting used to and is not for everyone. When it comes to zinc, however, oysters are the absolute leader: per 100 g they provide 90.8 mg of zinc, which is many times the daily requirement. And they have even more to offer: they also contain a good portion of vitamin D , which is very rare in food. They are also very rich in vitamin B12 , copper, selenium and iron. [1]
2. Liver
Liver is probably not for everyone, but it is also an excellent source of zinc. Calf liver, for example, contains 12 mg of zinc per 100g. Liver also provides a concentrated load of vitamin A and is rich in B vitamins , iron, selenium and copper . [2]
3. Pumpkin seeds
Pumpkin seeds also contain a considerable amount of zinc, with 10.3 mg of zinc per 100 g. They also provide plenty of magnesium, potassium and manganese. [3] So with a handful of pumpkin seeds in your muesli, yoghurt or salad, you are getting a good portion of valuable nutrients.
4. Meat
Meat also provides a good portion of zinc. Beef, for example, contains 10 mg of zinc per 100 g.
Beef is also a good source of B vitamins, iron and selenium. [4]
5. Shiitake mushrooms
Shiitake mushrooms are used in traditional Chinese medicine to treat many ailments. In terms of nutrients, they have a lot to offer. Dried shiitake mushrooms provide 8 mg of zinc per 100 g. They are also rich in B vitamins (except vitamin B12), magnesium , copper, manganese and selenium. [5]
6. Peanuts
Peanuts are also a good source of zinc: they contain 6.6 mg of zinc per 100 g. They also contain plenty of magnesium and manganese. [6] A peanut snack therefore provides many valuable minerals!
7. Cocoa
Cocoa is also a good source of zinc: 100 g provide 6.8 mg of the mineral. Cocoa is also rich in iron, magnesium, potassium and manganese. [7]
So chocolate is certainly rich in nutrients – provided the cocoa content is high enough. 85% chocolate tastes very pleasant and contains very little sugar.
8. Lentils
Lentils contain 4.8 mg of zinc per 100 g. They also provide a good portion of folic acid, iron, magnesium and manganese. [8] Legumes such as lentils are also an important source of protein for vegans .
9. Wild rice
Wild rice also provides plenty of zinc: it contains 6 mg of zinc per 100 g. Wild rice is also a good source of many other minerals such as magnesium, manganese and copper. [9]
10. Cheese
Cheese contains relatively high levels of zinc. Swiss cheese, for example, provides 4 mg of zinc per 100 g. Cheese is also rich in vitamin A, vitamin B2 and vitamin B12, calcium and selenium. [10] Dairy products such as cheese are also a good source of protein for vegetarians.
Conclusion: Zinc requirements vary individually
Oysters are by far the best source of zinc. But meat, nuts and seeds, legumes and cheese also provide plenty of zinc. However, phytic acid in legumes and grains binds zinc, making it more difficult to absorb. For this reason, vegans and vegetarians have an increased risk of zinc deficiency.
If zinc requirements cannot be met through food, supplementation with a high-quality zinc preparation may be useful.
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[1] Mollusks, oyster, eastern, wild, raw Nutrition Facts & Calories (self.com)
[2] Veal, variety meats and by-products, liver, raw [calf liver] Nutrition Facts & Calories (self.com)
[3] Seeds, pumpkin and squash seeds, whole, roasted, without salt Nutrition Facts & Calories (self.com)
[4] Beef, chuck, blade roast, separable lean only, trimmed to 0" fat, all grades, cooked, braised [Top Blade Steak] Nutrition Facts & Calories (self.com)
[5] Mushrooms, shiitake, dried Nutrition Facts & Calories (self.com)
[6] Peanuts, all types, oil-roasted, without salt Nutrition Facts & Calories (self.com)
[7] Cocoa, dry powder, unsweetened Nutrition Facts & Calories (self.com)
[8] Lentils, raw Nutrition Facts & Calories (self.com)
[9] Wild rice, raw Nutrition Facts & Calories (self.com)
[10] Cheese, swiss Nutrition Facts & Calories (self.com)

The most iodine-rich foods: How to meet your iodine needs
Iodine is an essential trace element that we must consume through our diet.
Iodized table salt was introduced in Germany to counteract iodine deficiency. Unfortunately, iodine deficiency is still widespread. Most people are not aware of this.
Here you can find out which foods are rich in iodine and how you can meet your needs.
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Iodine requirement
According to the German Nutrition Society (DGE), the daily requirement of iodine is 180 – 200 µg. Pregnant and breastfeeding women have an increased requirement of 230 µg and 260 µg respectively. [1]
Since the soil in Germany is low in iodine, a deficiency is unfortunately widespread. According to the Federal Institute for Risk Assessment, 30% of adults and 44% of children do not consume enough iodine.
In our detailed article on iodine you will learn more about this underestimated trace element.
Here is a list of foods that contain iodine: [2]
1. Iodized table salt
With 5070 µg of iodine per 100g, iodized table salt contains by far the most iodine per gram. But of course we only consume a few grams of salt per day. Nevertheless, iodized table salt is an important source of iodine.
2. Algae
Seaweed comes right after iodized table salt when it comes to iodine. They are particularly rich in iodine in dried form, as all the nutrients are then concentrated. Dried nori seaweed, for example, provides 2320 µg of iodine per 100 g.
However, iodine can be problematic in excessive amounts, so you should be careful when consuming algae. Too much iodine can be dangerous, especially for Hashimoto's disease.
If you are not a big fan of seaweed, there are also nutritional supplements that contain kelp brown algae . This is a very easy way to meet your iodine needs.
By the way, algae salt (salt with added algae) is a great alternative to iodized table salt. There is no difference in taste.
3. Eggs
Eggs are also a good source of iodine: they contain 49.2 µg of iodine per 100 g. You may be wondering how the iodine gets into the eggs if the chickens eat feed that comes from iodine-poor soil. A very legitimate question! In fact, iodine is added to chicken feed to increase the iodine content in eggs. In addition to iodized table salt, this is another measure to counteract iodine deficiency.
By the way, eggs are a great food in general. They provide high-quality protein, healthy fats and almost all vitamins and minerals in generous amounts.
4. Milk
Milk and dairy products are also a good source of iodine. Milk contains 34.3 µg of iodine per 100 g. This is because iodine is added to animal feed. Milk and dairy products also provide high-quality protein, calcium and numerous B vitamins. For vegetarians, dairy products are an important source of vitamin B12 .
5. Sea fish
Sea fish is also rich in iodine. Salmon, for example, provides 26.2 µg of iodine per 100g. This is no surprise, because the iodine-rich algae are at the bottom of the food chain: fish either eat algae or smaller fish that have eaten algae.
In addition to iodine, fish is also rich in valuable omega-3 fatty acids and a good source of magnesium, selenium and B vitamins .
6. Seafood
Seafood also provides plenty of iodine. Shrimps, for example, contain 14.7 µg of iodine per 100 g. They also provide an extra portion of vitamin B12 and numerous minerals such as zinc, selenium , magnesium and copper . [3]
7. Meat
Meat contains moderate amounts of iodine, but significantly less than fish, eggs and dairy products. Turkey, for example, provides 2.1 µg of iodine per 100 g. Turkey is also rich in B vitamins and the minerals zinc and selenium. [4]
8. Legumes
Legumes also provide some iodine, but comparatively little. Kidney beans, for example, contain 1.1 µg of iodine per 100g. Legumes are also a good source of B vitamins (except vitamin B12), plant-based iron, manganese, magnesium and potassium . [5] For vegans, they are also an important source of protein.
9. Nuts
Nuts contain a similar amount of iodine to pulses. For example, almonds provide 1 µg of iodine per 100 g. Nuts therefore do not contribute significantly to meeting iodine requirements. However, nuts provide many other valuable nutrients, such as B vitamins (except vitamin B12), vitamin E, manganese, copper, magnesium , potassium and zinc.
10. Vegetables
Unfortunately, due to the iodine-poor soil in Germany, vegetables hardly provide any iodine. Carrots, for example, contain 0.5 µg of iodine per 100g. But vegetables are of course a very important source of vitamins and minerals, as well as secondary plant substances .
Conclusion: Iodine deficiency is widespread
Unfortunately, iodine deficiency is widespread in Germany due to soils that are poor in iodine. The best sources of iodine are iodized table salt, algae, fish and seafood, as well as eggs and dairy products. Since iodine is mainly found in animal foods, vegans should rely more on algae as a source of iodine or take iodine as a dietary supplement .
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[1] https://www.dge.de/forschung/referenzwerte/jod/?L=
[2] https://www.ars.usda.gov/northeast-area/beltsville-md-bhnrc/beltsville-human-nutrition-research-center/methods-and-application-of-food-composition-laboratory/mafcl -site-pages/iodine/
[3] Crustaceans, shrimp, mixed species, raw Nutrition Facts & Calories (self.com)
[4] Turkey, all classes, meat only, raw Nutrition Facts & Calories (self.com)
[5] Beans, kidney, all types, mature seeds, raw Nutrition Facts & Calories (self.com)








